Gingival recession is a common clinical condition that leads to aesthetic dissatisfaction and dental hypersensitivity. Traditional surgical methods for soft tissue augmentation, while effective, are often invasive and require harvesting autogenous grafts. The search for minimally invasive alternatives has led to growing interest in injectable collagen-based biomaterials. Aim — to evaluate the clinical efficacy and safety of a xenogeneic collagen gel, “Collost,” for increasing soft tissue volume in the treatment of multiple gingival recessions. A 42-year-old female patient with multiple gingival recessions in the maxillary anterior region was treated. After initial professional hygiene, a 7% bovine collagen gel was injected into the soft tissues adjacent to the recessions according to a precise protocol, involving multiple injection points per tooth. A second injection was performed after 1 month to consolidate the result. Clinical outcomes were assessed immediately, at 2 weeks, and over a 12-month follow-up period. The procedure resulted in a significant increase in soft tissue volume and the elimination of gingival recessions, with a stable aesthetic outcome observed throughout the 12-month follow-up period. No adverse events, such as allergic reactions, inflammation, or material rejection, were reported. The protocol demonstrated good patient tolerance and a high safety profile. The use of xenogeneic collagen gel “Collost” is an effective and safe minimally invasive method for soft tissue augmentation in the treatment of gingival recessions. It provides a stable long-term result and represents a promising alternative to more invasive surgical techniques.

Keywords: gingival recession, collagen gel, soft tissue augmentation, xenogeneic material, minimally invasive technique.

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Kazumova A.B., Budaev G.G., Stroganova V.D., Dyachkova E.Yu. Use of Xenogeneic Collagen Gel for the Increase of Soft Tissue Volume in the Oral Cavity. Dentistry: Theory and Practice, 2025, vol. 3, no. 2, pp. 5–10. https://doi.org/10.65324/dtp001

The article provides an analysis of data on the use of modern platelet concentrates PRF in the practice of a dentist surgeon, High potential PRF, provides a physiological activation of reparative processes in the postoperative period and a powerful stimulation of the healing of post-operative injuries, the prevention of complications and increase the medical comfort of the patient. The research methodology was based on the analysis of scientific publications from the PubMed database. The available literature was analyzed on topics related to the use of L-PRF, A-PRF, A-PRF+, and T-PRF in dental extraction procedures, dental implantation, socket preservation, and final healing. The selection criteria included randomized clinical trials, cohort studies and systematic reviews dedicated to the clinical application of PRF in maxillofacial surgery. The results of the analysis demonstrate that PRF concentrates: accelerate osteogenesis and angiogenesis in the intervention area; reduce the frequency of postoperative complications (alveolitis, implant rejection); reduce the severity of pain syndrome and edema; increase the predictability of the results of bone reconstructive surgeries.

Keywords: platelet concentrates, platelets, leukocytes, PRF, surgical dentistry.

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Krasikov A.V., Bulanov S.I., Sofronov M.V., Kuznetsov M.V. Application of PRF platelet concentrates in surgical dentistry. Dentistry: Theory and Practice, 2025, vol. 3, no. 2, pp. 11–19. https://doi.org/10.65324/dtp002

The article presents a clinical case of complex dental rehabilitation of a patient with partial secondary adentia on the upper jaw with the active use of digital technologies. During the intervention, the following steps were performed sequentially: tooth extraction in positions 1.7, 1.5, 1.4, 1.3, 1.2, 1.1, 2.1, 2.2, 2.3, 2.4; installation of dental implants using a navigational surgical template that ensures high positioning accuracy; fixing of multi-unit abutments for reliable connection with orthopedic structure; installation of temporary orthopedic screw-type constructions, which immediately restored the function of chewing and the aesthetics of a smile. The use of a digital protocol made it possible to: minimize the trauma of the intervention through precise planning; reduce the overall rehabilitation time due to immediate loading of the implants; and ensure predictable results at all stages of treatment, from tooth extraction to the fixation of a temporary structure.

Keywords: igital dentistry, immediate dental implantation, immediate loading, minimally invasive extraction, guided surgical template.

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Kuznetsov M.V., Bulanov S.I., Sofronov M.V., Krasikov A.V., Volkov A.I. Comprehensive Dental Rehabilitation of a Patient Using Digital Technologies. Dentistry: Theory and Practice, 2025, vol. 3, no. 2, pp. 20–27. https://doi.org/10.65324/dtp003

One of the most significant problems in modern dentistry is marginal bone resorption (MBR) around dental implants. This complication poses a serious obstacle to the long-term success of implantation, directly affecting the stability of the structure and overall treatment outcomes. This review examines the key factors influencing MBR around dental implants through the lens of the immune theory as the dominant pathogenetic mechanism. Systemic diseases (with a focus on diabetes mellitus, arterial hypertension, and hyperlipidemia), iatrogenic factors (bone overheating, microtrauma during implant placement, or the ingress of microparticles/cement), and genetic predisposition (cytokine polymorphisms and innate recognition receptors) are considered as modifiers of the local immune response to the loss of marginal bone around implant. Data on the role of dysbiosis, titanium particles and ions, the TLR2/4–IRAK1–TRAF6 pathways, NOD1/2, and the RANKL/OPG signaling cascade, including the contribution of the NOTCH family, are summarized. Clinical implications for screening, planning, and supportive therapy are presented.

Keywords: marginal bone resorption, dental implant, immune imbalance, peri-implantitis.

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Zhukova K.D., Mizin I.N., Tretyak Ju.V., Gubaidullina A.R., Galyas A.I., Romanenko N.V. Marginal Bone Resorption as a Multifactorial Pathological Process. The Immune Theory of Marginal Bone Resorption Development: Literature Review. Dentistry: Theory and Practice, 2025, vol. 3, no. 2, pp. 28–34. https://doi.org/10.65324/dtp004